The moderation of an early intervention program for anxiety and depression by specific psychological symptoms

The current study examined the influence of a number of psychological factors on the effectiveness of an early intervention program targeting anxiety and depression in a non‐clinical sample of college students. The early intervention program comprised elements of the cognitive‐behavioral analysis system of psychotherapy (McCullough, 2000) delivered in a 2‐hour computer‐based educational program. Participants completed measures of depression, anxiety, and general distress prior to the intervention program and then again 8 weeks later. Additionally, participants were assessed for past major depression, sleep related difficulties, a number of anxiety disorders, and suicide ideation. Moderation of the effectiveness of the early intervention program by these factors depended on the dependent variable of interest, specifically: the effectiveness of the intervention program on symptoms of depression was moderated by insomnia; symptoms of anxiety by past post‐traumatic stress disorder (PTSD) and specific phobia as well as sleep problems related to nightmares; and symptoms of general negative affect by social phobia and suicide ideation. Implications are discussed. © 2009 Wiley Periodicals, Inc. J Clin Psychol 65:1–15, 2009.