Open AccessThe immunologic changes during different phases of intestinal anastomotic healing
Author(s) -
Zhang Feng,
Qiao Song,
Li Chunqiao,
Wu Bo,
Reischl Stefan,
Neumann PhilippAlexander
Publication year - 2020
Publication title -
journal of clinical laboratory analysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.536
H-Index - 50
eISSN - 1098-2825
pISSN - 0887-8013
DOI - 10.1002/jcla.23493
Subject(s) - anastomosis , immune system , phase (matter) , immunology , medicine , surgery , chemistry , organic chemistry
Intestinal anatomosis is a complex and multicellular process that involving three overlapped phases: exudative phase, proliferative phase, and reparative phase. Undisturbed anastomotic healings are crucial for the recovery of patients after operations but unsuccessful healings are linked with a considerable mortality. This time, we concentrate on the immunologic changes during different phases of intestinal anastomotic healing and select several major immune cells and cytokines of each phase to get a better understanding of these immunologic changes in different phases, which will be significant for more precise therapy strategies in anastomoses.