Open AccessSimple strategy for sensitive detection of dopamine using CdTe QD s modified glassy carbon electrode
Author(s) -
Yu Hongwei,
Zhang Ze,
Jiang Jinghui,
Pan Hongzhi,
Chang Dong
Publication year - 2018
Publication title -
journal of clinical laboratory analysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.536
H-Index - 50
eISSN - 1098-2825
pISSN - 0887-8013
DOI - 10.1002/jcla.22320
Subject(s) - differential pulse voltammetry , detection limit , quantum dot , biosensor , electrochemistry , electrode , dopamine , cadmium telluride photovoltaics , materials science , linear range , analytical chemistry (journal) , chemistry , cyclic voltammetry , nanotechnology , chromatography , neuroscience , biology
Background Cellular and brain metabolism of dopamine can be correlated with a number of neurodegenerative disorders, our study was to explore a simple and efficient method to detect dopamine in real samples. Methods A new quantum dots (CdTe QD s) could be prepared using the hydrothermal method, the electrochemical biosensor was established by dropping CdTe QD s on the surface of glassy carbon electrode ( GCE ). Results The CdTe QD s/ GCE exhibited the excellent electrochemical catalytic activity toward dopamine ( DA ) with good stability and high sensitivity in presence of interfering substances. The detection limit of DA was calculated by differential pulse voltammetry ( DPV ) as low as 0.3 μmol L −1 with a linear dynamic range of 1 μmol L −1 to 400 μmol L −1 . Conclusion In this paper, the proposed electrochemical biosensor could be effectively used for the direct and rapid detection of DA in human serum and urine samples.