
Association of ADIPOQ , leptin, LEPR , and resistin polymorphisms with obesity parameters in Hammam Sousse Sahloul Heart Study
Author(s) -
Zayani Nesrine,
Omezzine Asma,
Boumaiza Imen,
Achour Ons,
Rebhi Lamia,
Rejeb Jihen,
Ben Rejeb Nabila,
Ben Abdelaziz Ahmed,
Bouslama Ali
Publication year - 2017
Publication title -
journal of clinical laboratory analysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.536
H-Index - 50
eISSN - 1098-2825
pISSN - 0887-8013
DOI - 10.1002/jcla.22148
Subject(s) - resistin , adipokine , adiponectin , leptin receptor , medicine , leptin , endocrinology , genotyping , obesity , genotype , adipose tissue , biology , insulin resistance , genetics , gene
Background Adipose tissue is an important endocrine organ that secretes a number of adipokines, such as adiponectin ( ADIPOQ ), leptin ( LEP ), leptin receptor ( LEPR ), and resistin ( RETN ) which may be implicated in obesity. Some adipokines’ polymorphisms of genes might influence their concentrations and/or activities. Our aim was to study the relationship between seven SNP s in ADIPOQ (+45T