Open AccessReference values for kaolin‐activated thromboelastography in volunteers of Anhui Province in China
Author(s) -
Sun JunBo,
Bian MaoHong,
Zhong Tao,
Lu YingYu,
Zhu BangQiang,
Wen HuiQin,
Hu HaiLiang
Publication year - 2017
Publication title -
journal of clinical laboratory analysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.536
H-Index - 50
eISSN - 1098-2825
pISSN - 0887-8013
DOI - 10.1002/jcla.22128
Subject(s) - thromboelastography , reference values , medicine , population , coagulation , environmental health
Background The assessment of the coagulation status using thromboelastography (TEG) in Chinese population has less been reported. This study aimed to establish reliable reference values for kaolin‐activated TEG in Chinese volunteers. Methods A total of 1681 Chinese adult individuals were recruited for this study. The reference individuals were stratified by gender and age, and the TEG values were measured on the basis of strict quality control. The 95% reference values were determined using nonparametric statistical methods. Results The sex‐related 95% reference values were reaction time (R):4.2‐8.7 minutes; clotting time (K): 1.2‐3.2 minutes; alpha angle (α): 47.0‐72.3 degree; maximum amplitude (MA): 49.1‐70.5 mm for males, and R: 3.7‐9.0 minutes; K: 1.0‐3.2 minutes; α: 48.4‐74.4 degree; MA: 46.8‐72.4 mm for females. Also, the TEG parameters indicated a relatively more hypercoagulable profile in both female and elder groups. Conclusions This study established the reference values for kaolin‐activated TEG in the target Chinese population, which might provide a reference for both clinical and laboratory studies.