Open AccessEvaluation of the Alere NT‐proBNP Test for Point of Care Testing
Author(s) -
Khezri Banafsheh Seyyed,
Carlsson Lena,
Larsson Anders
Publication year - 2016
Publication title -
journal of clinical laboratory analysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.536
H-Index - 50
eISSN - 1098-2825
pISSN - 0887-8013
DOI - 10.1002/jcla.21853
Subject(s) - point of care testing , medicine , point of care , primary care , immunology , pathology , family medicine
Background The object of the study was to evaluate the Alere point of care NT‐proBNP assay as a suitable alternative to the central laboratory method to provide short test turnaround times in primary care. Method Blood NT‐proBNP results obtained with the Alere assay ( n = 100) were compared with s erum NT‐proBNP results analyzed by a Cobas 8000 analyzer (Roche Diagnostics, Mannheim, Germany). Results There was a good agreement between the two NT‐proBNP methods when used as a rule‐out test for heart failure (HF) and the cut‐off value <300 ng/l. A total of 47 samples gave values <300 ng/L with both methods and 51 samples gave values >300 with both methods. Thus, there was an agreement for 98% of the samples. Conclusions The study shows that the Alere NT‐proBNP assay could be used in primary care permitting rapid NT‐proBNP testing to rule out HF.