Open AccessModerate‐Intensity Single Exercise Session Does Not Induce Renal Damage
Author(s) -
Hiraki Koji,
KamijoIkemori Atsuko,
Yasuda Takashi,
Hotta Chiharu,
Izawa Kazuhiro P.,
Watanabe Satoshi,
Sugaya Takeshi,
Kimura Kenjiro
Publication year - 2013
Publication title -
journal of clinical laboratory analysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.536
H-Index - 50
eISSN - 1098-2825
pISSN - 0887-8013
DOI - 10.1002/jcla.21579
Subject(s) - creatinine , medicine , renal function , urinary system , urology , kidney disease , urine , albumin , kidney , endocrinology
Background The aim of this study was to determine whether a single moderate‐intensity exercise session induces renal injury based on various parameters that reflect kidney dysfunction, including urinary L‐type fatty acid‐binding protein ( L ‐ FABP ). Methods Adult outpatients ( n = 31) with chronic kidney disease (CKD) not receiving renal replacement therapy participated in this study. Urine was collected before and after a single 20‐min moderate‐intensity exercise session. Urinary levels of L ‐ FABP , albumin, N ‐acetyl‐β‐ d ‐glucosaminidase ( NAG ), and α1‐microglobrin (α1 MG ) were measured. In addition, 12 patients with estimated glomerular filtration fraction less than 30 ml/min/1.73 ml 2 were selected from all patients and evaluated using the same analysis. Results Urinary values of L ‐ FABP , albumin, NAG , and α1 MG did not increase significantly after exercise compared with before exercise (urinary L ‐ FABP , from 8.3 to 9.4 μg/g of creatinine; urinary albumin, from 293.1 to 333.7 mg/g of creatinine; urinary NAG , from 9.2 to 8.2 U/g of creatinine; urinary α1 MG , from 11.4 to 9.8 mg/g of creatinine, not significant). Similar findings were seen in all patients, regardless of degree of renal dysfunction. Conclusions A single session of moderate‐intensity exercise was not associated with an increase in renal parameters used to assess renal damage.