Open AccessEvaluation of BD vacutainer SST ™ II plus tubes for common tumor marker tests by Roche Diagnostics Modular E 170 analyzer
Author(s) -
Li Zhiyan,
Feng Zhenru,
Yan Cunling,
Yan Rong
Publication year - 2010
Publication title -
journal of clinical laboratory analysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.536
H-Index - 50
eISSN - 1098-2825
pISSN - 0887-8013
DOI - 10.1002/jcla.20422
Subject(s) - vacutainer , chromatography , analyte , tumor marker , hemolysis , separator (oil production) , blood collection , chemistry , medicine , cancer , physics , emergency medicine , thermodynamics
Serum separator tubes were introduced 35 years ago and were widely used in the clinical laboratory in China for routine collection of blood because of providing a closed system that allowed for collection, transport, processing, sampling, and storage of specimens. This type of tubes facilitated rapid separation of serum from cellular constituents of blood and also prevented hemolysis upon prolonged storage. However, there were some limitations associated with gel tubes (i.e., gel and analyte stability). In order to circumvent these problems, BD released a new serum separator tube containing a new gel (BD SST ™ II Plus). We investigated theperformance of BD SST ™ II Plus tubes for tumor marker tests using BD Serum Glass tubes as controls. Equivalence between the BD SST ™ II Plus and BD Serum Glass tubes was demonstrated for all analytes at initial time. Also, all analytes remained stable when stored in BD SST ™ II Plus tubes up to 72 hr. Concentration of neuron‐specific enolase tended to increase with preservation time up to 72 hr in BD Serum Glass tubes. We conclude that BD SST ™ II Plus was suitable for collection of blood and storage of serum for tumor marker tests. J. Clin. Lab. Anal. 24:418–421, 2010. © 2010 Wiley‐Liss, Inc.