Open AccessSpread of nontuberculous mycobacteria from 1993 to 2006 in Koreans
Author(s) -
Ryoo Sung Weon,
Shin Sonya,
Shim Myungshup,
Park YoonSung,
Lew Woo Jin,
Park SueNie,
Park Young Kil,
Kang Seongman
Publication year - 2008
Publication title -
journal of clinical laboratory analysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.536
H-Index - 50
eISSN - 1098-2825
pISSN - 0887-8013
DOI - 10.1002/jcla.20278
Subject(s) - nontuberculous mycobacteria , mycobacterium avium complex , mycobacterium kansasii , medicine , lung disease , veterinary medicine , microbiology and biotechnology , biology , mycobacterium , lung , pathology , tuberculosis
In Korea, the prevalence of nontuberculous mycobacterial (NTM) pulmonary disease has risen, observed primarily in immunocompetent patients with or without preexisting lung disease. The purpose of this study was to determine the frequency of various species of NTM isolates from respiratory specimens in a single institution over a 14‐year period in Korea. All samples referred to our reference laboratory over a 14‐year period in Korea were analyzed. From 1993 to 2000 our laboratory used conventional NTM identification methods, and from 2001 we adapted PCR‐restrictionfragment length polymorphism analysis(PRA). A total of 17,915 isolates were collected from 1993 to 2006. The most frequently isolated organisms were M. avium complex ( n =11,705, 65%), M. abscessus ( n =2,076, 11.59%), M. fortuitum complex ( n =1,279, 7.14%). M. chelonae complex ( n =1,134, 6.33%), M. kansasii ( n =762, 4.25%), M. szulgai ( n =139, 0.78%), M. celatum ( n =87, 0.49%), M. scrofulaceum ( n =18, 0.10%) and M. marium ( n =11, 0.06%). J. Clin. Lab. Anal. 22:415–420, 2008. © 2008 Wiley‐Liss, Inc.