Open AccessModern aspects and requirements for the standardization of immunoassays for human plasma proteins
Author(s) -
Baudner S.
Publication year - 1993
Publication title -
journal of clinical laboratory analysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.536
H-Index - 50
eISSN - 1098-2825
pISSN - 0887-8013
DOI - 10.1002/jcla.1860070508
Subject(s) - standardization , human plasma , engineering ethics , data science , engineering , computer science , chemistry , political science , chromatography , law
Some fundamental problems are summarized for an optimal standardization of protein determination in immunoassays. The relationship between a measurement signal in an immunoassay and the protein value followed by that is complicated and is explained on the basis of two immunochemical postulates and of two nonimmunochemical influences for which four postulates are derived.