Open AccessAlloalbumin in cerebrospinal fluid: Report of a case and remarks on physiopathology
Author(s) -
Banfi Giuseppe,
Marinelli Marcello,
Comi Giancarlo,
Martinelli Vittorio,
Bonini Pierangelo
Publication year - 1990
Publication title -
journal of clinical laboratory analysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.536
H-Index - 50
eISSN - 1098-2825
pISSN - 0887-8013
DOI - 10.1002/jcla.1860040512
Subject(s) - cerebrospinal fluid , isoelectric focusing , immunofixation , pathophysiology , pathology , cerebrospinal fluid proteins , medicine , chemistry , immunology , biochemistry , antibody , monoclonal , monoclonal antibody , enzyme
Alloalbumin Tagliacozzo(313Lys→ Asn) was detected in the cerebrospinal fluid of a 27‐yr‐old woman. We studied this rare finding by means of high‐resolution electrophoresis, isoelectric focusing, and immunofixation. We herein discuss the importance of molecular mass versus superficial electrical charge in the transfer of plasma proteins through the blood‐brain barrier.