Open AccessAntibodies to the metacestode of taenia solium in the saliva from patients with neurocysticercosis
Author(s) -
Acosta E.
Publication year - 1990
Publication title -
journal of clinical laboratory analysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.536
H-Index - 50
eISSN - 1098-2825
pISSN - 0887-8013
DOI - 10.1002/jcla.1860040204
Subject(s) - neurocysticercosis , metacestode , taenia solium , saliva , cysticercosis , antibody , medicine , immunology , pathology , helminths , cestoda
IgG antibodies to antigens of Taenia solium metacestodes were detected in saliva samples from patients with intracerebral cysticercosis by means of an enzyme‐linked immunosorbent assay (ELISA). When compared for IgG antibody activity, saliva samples from patients with various nonparasitic neurological disorders and from clinically healthy individuals yielded significantly lower (p < 0.001) absorbance values than saliva samples from patients with neurocysticercosis. However, no differences were observed in IgA anti– T. sodium activity between patients with neurocysticercosis and controls. These results indicate that the detection of anticysticercus IgG antibodies in saliva by means of ELISA may be of value in the diagnosis of neurocysticercosis. Moreover, collection of saliva provides a noninvasive sampling method for immuno‐epidemiological surveys on this disease.