Open AccessDetection of oncogene‐related proteins with site‐directed monoclonal antibody probes
Author(s) -
Niman Henry L.
Publication year - 1987
Publication title -
journal of clinical laboratory analysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.536
H-Index - 50
eISSN - 1098-2825
pISSN - 0887-8013
DOI - 10.1002/jcla.1860010105
Subject(s) - monoclonal antibody , oncogene , computational biology , biology , oncogene proteins , antibody , microbiology and biotechnology , genetics , gene , regulation of gene expression , cell cycle
Sequences of oncogenes define related families and provide a large data bank for the production of synthetic peptides. These peptides can be used to produce site‐directed monoclonal antibody probes, which identify oncogene‐encoded and oncogene‐related proteins. The creation and utilization of these probes for clinical laboratory analysis are discussed.