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Kinetics and thermodynamics adsorption of Oxazepam drug on the multi‐walled carbon nanotube
Author(s) -
Mohammadi Majid,
Vadi Mehdi,
Bagehri Narges,
Shekoohi Khadijeh,
Younessi Floura
Publication year - 2021
Publication title -
journal of the chinese chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 45
eISSN - 2192-6549
pISSN - 0009-4536
DOI - 10.1002/jccs.202000407
Subject(s) - chemistry , adsorption , freundlich equation , carbon nanotube , kinetics , langmuir adsorption model , langmuir , nuclear chemistry , thermodynamics , chromatography , chemical engineering , organic chemistry , physics , quantum mechanics , engineering
Nowadays, it is admitted to using of suitable carrier results in improving drug delivery such as nanotubes. So, multi‐walled carbon nanotube (MWCNTs) has been proposed as a carrier (adsorbent) to improve the neurological Oxazepam (OZ) drug delivery. Freundlich, Temkin, and Langmuir isotherm models have been used in order to do assay adsorption of the OZ on the MWCNT. The maximum value of the isotherm constant ( b = 0.14 L/mg) at 303 K temperature indicates stronger (better) adsorption of the OZ on the MWCNT surface in low concentrations (20 mg/L) and acidic pH; in fact, increasing of pH led to decreasing adsorption (60 → 35.91 mg/g) and dehydrogenation of the OZ drug. Reaching to the equilibrium state after 90 min and negative value of the ∆ H (−41.57 kJ/mol) shows that the OZ adsorption has fast kinetic and exothermic processes. These issues imply depending of the OZ adsorption on the OZ concentration and the weight of adsorbent in the adsorption process.