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Retracted: Zn( II )‐based complex: Photocatalytic degradation of methylene blue and biological activity on the brain damage caused by cerebral hemorrhage by reducing the thrombin content
Author(s) -
Shi YongWei,
Su Jing,
Chen XiaoChang,
Yu YaDong
Publication year - 2021
Publication title -
journal of the chinese chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 45
eISSN - 2192-6549
pISSN - 0009-4536
DOI - 10.1002/jccs.202000252
Subject(s) - chemistry , methylene blue , degradation (telecommunications) , photocatalysis , benzene , western blot , nuclear chemistry , hydrothermal circulation , methylene , ligand (biochemistry) , polymer chemistry , photochemistry , medicinal chemistry , biochemistry , receptor , organic chemistry , catalysis , chemical engineering , telecommunications , computer science , engineering , gene
Through applying the mixed‐ligand method, a new coordination polymer (CP) based on Zn(II) ions as metal nodes was synthesized under the hydrothermal reaction conditions, and its chemical formula is {[Zn(L) 0.5 (1,4‐bib)]·H 2 O} n ( 1 ) (H 4 L = 1,2,4,5‐cyclohexanetetracarboxylic acid and 1,4‐bib = 1,4‐bis[1 H ‐imidazol‐1‐yl]benzene). The photophysical research reflected that the complex 1 is a kind of potential semiconductor material. In addition, under the ultraviolet irradiation, complex 1 has high photocatalytic degradation efficiency for methylene blue (MB), and it reveals excellent recoverability and stability. Furthermore, the biological activity of the compound against brain damage caused by cerebral hemorrhage was evaluated. The real‐time Reverse Transcription Polymerase Chain Reaction (RT‐PCR) method was conducted firstly to determine the prothrombin expression levels. Next, the inflammatory response in the brain tissue was assessed by determining the activation level of nuclear factor kappa‐B (NF‐κB) with western blot.