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Exploring recent developments on 1,2,4‐triazole: Synthesis and biological applications
Author(s) -
Sathyanarayana Reshma,
Poojary Boja
Publication year - 2020
Publication title -
journal of the chinese chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 45
eISSN - 2192-6549
pISSN - 0009-4536
DOI - 10.1002/jccs.201900304
Subject(s) - chemistry , triazole , combinatorial chemistry , 1,2,4 triazole , nanotechnology , organic chemistry , materials science
Triazoles are nitrogen‐bearing heterocycles. In the last few decades, researchers have focused on fused heterocycles, as they have better pharmacological effect compared to triazoles alone. Among the two isomers of triazole, this article aims to explore the work carried out on 1,2,4‐triazole and N ‐bridged heterocycles derived from 1,2,4‐triazole in last 18 years, highlight different synthetic pathways, and present a brief summary of the different biological activities possessed by 1,2,4‐triazole derivatives. The information collected in this article is expected to help researchers to discover novel therapeutic agents for better applications in the field of pharmaceutical science.