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Deoxypyridinoline‐bioinspired supramolecular antibacterial salts with a C—H⋯O hydrogen‐bonded tetrameric host to construct the helical scaffold and sheet structures: The importance of rotational flexibility, anion shapes, and robust C—H⋯O hydrogen bonding
Author(s) -
Hung HuiYu,
Hsu ChingI,
Wu CheKai,
Wen HsinYi,
Lee KwangMing
Publication year - 2020
Publication title -
journal of the chinese chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 45
eISSN - 2192-6549
pISSN - 0009-4536
DOI - 10.1002/jccs.201900190
Subject(s) - chemistry , supramolecular chemistry , hydrogen bond , scaffold , crystallography , ion , flexibility (engineering) , stereochemistry , organic chemistry , crystal structure , molecule , medicine , statistics , mathematics , biomedical engineering
A new flexible hydrogen‐bonded supramolecular host based on two deoxypyridinoline‐bioinspired 6‐hexanoic acid‐substituted 3‐hydroxypyridinium cations that adopt the twist and planar conformations and construct the orthogonal single helical scaffold and sheet structures with the triangular NO 3 − and spherical Br − guest anions, respectively. The results demonstrated not only the importance of rotational flexibility, anion shapes, and robust C—H⋯O hydrogen bonding, but also the good antibacterial activity with the potential antibacterial application.