Premium
A surfactant‐free synthesis of the silica nanosphere‐supported ultrafine silver nanoparticles and their antibacterial effects
Author(s) -
Shen Qihui,
Shan Yixuan,
Lü Yang,
Xue Peng,
Shu Xian,
Li Dongmei,
Liu Yan,
Liu Xiaoyang
Publication year - 2019
Publication title -
journal of the chinese chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 45
eISSN - 2192-6549
pISSN - 0009-4536
DOI - 10.1002/jccs.201900105
Subject(s) - chemistry , pulmonary surfactant , silver nanoparticle , antibacterial activity , nuclear chemistry , nanoparticle , chemical engineering , nanotechnology , surface modification , scanning electron microscope , bacteria , materials science , biochemistry , biology , engineering , genetics , composite material
In this study, a facile, efficient, and surfactant‐free method to synthesize silica nanosphere‐supported ultrafine silver nanoparticles (AgNPs) (~2.5 nm) was developed, and their antibacterial effects were investigated. In the synthesis process, the hydrolysis of 3‐mercaptopropyltrimethoxysilane was adopted to provide thiol groups and in situ reduce Ag + to Ag 0 for ultrafine AgNPs formation on the surface of the silica nanosphere. Electron microscopy characterization of the complex formed revealed that the ultrafine AgNPs were not agglomerated and grow without any surfactants because there were no excess electrons transported from the shell to reduce the silver ions to silver atoms. The antibacterial effects of the supported ultrafine AgNPs with the surfactant‐free surface were evaluated against the Escherichia coli even at very low dosage. After incubation with 20 μg/mL silica‐supported AgNPs up to 120 min, 99.7% of the E. coli were inactivated, according to the bacterial viability measured by flow cytometry.