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Fe 3 O 4 @SiO 2 @sulfated boric acid as superparamagnetic and recyclable nanocatalyst‐assisted, one‐pot, pseudo four‐component synthesis of 5‐amino‐2‐aryl‐3 H ‐chromeno[4,3,2‐ de ][1,6]naphthyridine‐4‐carbonitrile derivatives
Author(s) -
Khosravi Zeynab,
Mohammadi Hadi,
Shaterian Hamid Reza
Publication year - 2019
Publication title -
journal of the chinese chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 45
eISSN - 2192-6549
pISSN - 0009-4536
DOI - 10.1002/jccs.201900044
Subject(s) - chemistry , boric acid , malononitrile , catalysis , reusability , sulfation , superparamagnetism , heterogeneous catalysis , solvent , nuclear chemistry , organic chemistry , inorganic chemistry , biochemistry , physics , magnetization , software , quantum mechanics , computer science , magnetic field , programming language
Abstract The catalytic performance of the superparamagnetic nanocatalyst Fe 3 O 4 @SiO 2 @Sulfated boric acid as a green, recyclable, and acidic solid catalyst in the synthesis of chromeno[4,3,2‐ de ][1,6]naphthyridine derivatives has been studied. Chromeno[4,3,2‐ de ][1,6]naphthyridine derivatives via a pseudo four‐component reaction from aromatic aldehydes (1 mmol), malononitrile (2 mmol), and 2′‐hydroxyacetophenone in the presence of Fe 3 O 4 @SiO 2 @Sulfated boric acid (0.004 g) as a nanocatalyst in 3 mL of water as a green solvent at 80°C has been synthesized. The advantages of this method are higher product yields in shorter reaction times, easy recyclability and reusability of the catalyst, and easy work‐up procedures. The nanocatalyst was reused at least six times. The nanocatalyst retained its stability in the reaction, and after reusability, it was separated easily from the reaction by an external magnet.