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TiO 2 ‐nanoparticles as efficient catalysts for the synthesis of pyridine dicarbonitriles
Author(s) -
ShamsNajafi Sayyed Jalal,
Gholizadeh Mostafa,
Ahmadpour Ali
Publication year - 2019
Publication title -
journal of the chinese chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 45
eISSN - 2192-6549
pISSN - 0009-4536
DOI - 10.1002/jccs.201900041
Subject(s) - chemistry , pyridine , thiophenol , catalysis , malononitrile , aryl , nanoparticle , combinatorial chemistry , organic chemistry , nanotechnology , alkyl , materials science
The catalytic effects of two forms of nano‐TiO 2 , which are prepared via an ordinary or a magnetized process, are investigated in the synthesis of pyridine dicarbonitriles by one‐pot multicomponent reaction of 4‐methyl thiophenol, malononitrile, and aryl aldehydes. The results have shown that both prepared nano‐TiO 2 exhibited high catalytic activities toward the synthesis of pyridine dicarbonitrile derivatives but the nano‐TiO 2 , which is prepared via a magnetized process, has shown better catalytic activity. Furthermore, this new catalytic method for the synthesis of pyridine dicarbonitriles provides rapid access to the desired compounds in high yields and so a simple work‐up procedure in the presence of water at room temperature. Therefore, this method represents a significant improvement incompatible of the other methods that are available for the synthesis of pyridine dicarbonitriles.