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Cover: Journal of the Chinese Chemical Society 9/2018
Publication year - 2018
Publication title -
journal of the chinese chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 45
eISSN - 2192-6549
pISSN - 0009-4536
DOI - 10.1002/jccs.201880901
Subject(s) - chemistry , tyrosinase , chelation , cover (algebra) , magnetic nanoparticles , copper , nanotechnology , enzyme , combinatorial chemistry , nanoparticle , biochemistry , organic chemistry , mechanical engineering , materials science , engineering
In this paper , tyrosinase‐immobilized magnetic nanoparticles (TRY‐MNPs) and 96 well homemade magnetic microplate are used for quickly screening tyrosinase inhibitors. True inhibitors are identified, without interference from antioxidants. Whether the inhibitor is a copper ion chelator or a specific enzyme binder can be identified by adding Cu 2+ to restore the activity of TRY‐MNPs. More details will be discussed by Dr. Hweiyan Tsai and her co‐workers on page 1075–1081 in this issue.