Premium
MgSiO 3 nanoparticle‐catalyzed 1,3‐dipolar cycloaddition reactions in the synthesis of novel spiroindane‐1,3‐diones derived from substituted chalcones
Author(s) -
Hegde Subramanya Gopal,
Koodlur Lokesh,
Reddy Suman Y.,
Narayanarao Manjunatha
Publication year - 2019
Publication title -
journal of the chinese chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 45
eISSN - 2192-6549
pISSN - 0009-4536
DOI - 10.1002/jccs.201800445
Subject(s) - chemistry , cycloaddition , chalcone , sarcosine , catalysis , ninhydrin , yield (engineering) , microwave irradiation , 1,3 dipolar cycloaddition , nanoparticle , combinatorial chemistry , organic chemistry , nanotechnology , glycine , amino acid , biochemistry , materials science , metallurgy
Employment of metal nanoparticles has been one of the most promising synthetic strategies for a number of chemical transformations. New spiroindane‐1,3‐diones were synthesized through [3 + 2] cycloaddition in moderate to high yields by a three‐component reaction of heterocyclic chalcone derivatives, ninhydrin, and sarcosine/L‐proline. The presence of heterogenous MgSiO 3 nanoparticles (NPs) under microwave irradiation showed a robust effect in improving the yield of the desired products. Furthermore, the catalyst may be recovered and reused without significant loss of activity.