Premium
Synthesis of multi‐functionalized quinolines and 1,2‐dihydroquinolines through FeCl 3 ‐mediated reactions of carbonyl compounds with 2‐vinylanilines
Author(s) -
Liu Sha,
Li Gaoqiang,
Xu Feng
Publication year - 2018
Publication title -
journal of the chinese chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 45
eISSN - 2192-6549
pISSN - 0009-4536
DOI - 10.1002/jccs.201800001
Subject(s) - chemistry , catalysis , functional group , combinatorial chemistry , metal carbonyl , organic chemistry , metal , polymer
A facile and efficient approach toward the synthesis of functionalized quinolines and 1,2‐dihydroquinolines from carbonyl compounds and 2‐vinylanilines is described. The protocol utilizes the nonhazardous and less expensive FeCl 3 as catalyst with wide functional group tolerance and avoiding heavy metal impurities in the products.