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MNPs‐NHC 6 H 4 SO 3 H as high‐performance catalyst for the synthesis of 1,4‐diazepines containing tetrazole ring under microwave irradiation
Author(s) -
SafaeiGhomi Javad,
PaymardSamani Soleiman,
ShahbaziAlavi Hossein
Publication year - 2018
Publication title -
journal of the chinese chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 45
eISSN - 2192-6549
pISSN - 0009-4536
DOI - 10.1002/jccs.201700349
Subject(s) - tetrazole , catalysis , chemistry , thermogravimetric analysis , dynamic light scattering , ring (chemistry) , scanning electron microscope , fourier transform infrared spectroscopy , nuclear chemistry , spectroscopy , infrared spectroscopy , microwave irradiation , chemical engineering , nanoparticle , organic chemistry , nanotechnology , materials science , physics , quantum mechanics , engineering , composite material
MNPs‐NHC 6 H 4 SO 3 H as an efficient catalyst was prepared and characterized by X‐ray diffraction (XRD), Fourier transform infrared spectroscopy (FT‐IR), scanning electron microscopy (SEM), vibrating sample magnetometer (VSM), DLS dynamic light scattering (DLS), and thermogravimetric analysis (TGA) techniques. The catalytic activity of MNPs‐NHC 6 H 4 SO 3 H was investigated in the synthesis of 1,4‐diazepines containing the tetrazole ring via a four‐component reaction under microwave irradiation. The heterogeneous catalyst could be recovered easily and reused six times without significant loss of its catalytic activity. The present work demonstrates the advantages of microwave irradiation‐assisted heterogeneous catalysis in the synthesis of 1,4‐diazepines containing the tetrazole ring, compounds that generate great attention in many applications, particularly in medicinal chemistry and drug discovery.