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Overview on Developed Synthesis Methods of Triazepane Heterocycles
Author(s) -
Mohammadi Zeydi Masoud,
Mahmoodi Nosrat O.
Publication year - 2017
Publication title -
journal of the chinese chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 45
eISSN - 2192-6549
pISSN - 0009-4536
DOI - 10.1002/jccs.201700069
Subject(s) - chemistry , tap water , ring (chemistry) , combinatorial chemistry , organic chemistry , environmental engineering , engineering
Triazepanes are important seven‐membered heterocyclic compounds with nitrogen at different positions in the ring, and have many pharmaceutical activities. Compounds with the triazepane core have attracted much attention as a result of their interesting biological properties. A study of the literature shows that there are various methods for the preparation of triazepanes. In this review, we have classified the methods based on the nitrogen position in the final triazepine products into four triazepine classes, namely TAP ‐1,2,3, TAP ‐1,2,4, TAP ‐1,2,5, and TAP ‐1,3,5.