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Catalytic Synthesis of Chalcones and Pyrazolines Using Nanorod Vanadatesulfuric Acid: An Efficient and Reusable Catalyst
Author(s) -
NasrEsfahani Masoud,
Daghaghale Mona,
Taei Mahbube
Publication year - 2017
Publication title -
journal of the chinese chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 45
eISSN - 2192-6549
pISSN - 0009-4536
DOI - 10.1002/jccs.201600157
Subject(s) - chemistry , catalysis , nanorod , combinatorial chemistry , organic chemistry , chemical engineering , engineering
Nanorod vanadatesulfuric acid ( VSA NRs ), as a recyclable and ecologically benign catalyst, was used for the one‐pot synthesis of chalcones and 1,3,5‐triaryl‐2‐pyrazolines ( TAPs ). Chalcones were prepared via the condensation of substituted acetophenones with aryl‐aldehydes under solvent‐free conditions. Subsequently, the synthesized chalcones were used for the catalytic synthesis of TAPs via two‐component condensation with phenyl hydrazine in refluxing ethanol. VSA is easily prepared by a simple reaction of chlorosulfonic acid and sodium metavanadate of high purity. Compared to conventional procedures, the present protocol offers several advantages such as simplicity of the procedure, appropriate reaction times, high to excellent yields, easily work‐up, recoverability, and reusability of the catalyst, and simple purification of the products.