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Synthesis of Pyrimidinone and 5‐unsubstituted 4, 6‐diarylpyrimidine‐2(1 H )‐ones by Using Nano Magnetic Catalyst under Solvent Free Condition
Author(s) -
Amoozadeh Ali,
Azhari Saeede,
Kolvari Eskandar,
Otokesh Somayeh
Publication year - 2015
Publication title -
journal of the chinese chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 45
eISSN - 2192-6549
pISSN - 0009-4536
DOI - 10.1002/jccs.201500120
Subject(s) - chemistry , pyrimidinones , catalysis , cyclopentanone , acetophenone , nano , solvent , sulfonic acid , organic chemistry , magnetic nanoparticles , combinatorial chemistry , nanoparticle , nanotechnology , chemical engineering , materials science , engineering
Nano magnetic‐supported sulfonic acid is found to be a powerful and reusable heterogeneous catalyst for the efficient synthesis of pyrimidinones. In this study we use various ketones such as acetophenone and cyclopentanone instead of β‐keto ester in one‐pot synthesis of pyrimidinone at biginelli like reaction. Our objective is to improve conditions for the synthesis of multicomponent reactions using nano magnetic catalyst under solvent free condition. A number of excellent and significant results have been developed that lead our perspective understanding the effect of the magnetic nanoparticles when they are used as catalysts.