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One‐pot Solvent Free Synthesis of Some Tert‐indolylmethane Amine Derivatives by Fe(HSO 4 ) 3 as a Recyclable Catalyst
Author(s) -
Rahimizadeh Mohammad,
Eshghi Hossein,
MokaberEsfahani Majid,
Gholizadeh Mostafa
Publication year - 2014
Publication title -
journal of the chinese chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 45
eISSN - 2192-6549
pISSN - 0009-4536
DOI - 10.1002/jccs.201400192
Subject(s) - chemistry , aniline , catalysis , aldehyde , indole test , amine gas treating , solvent , alkyl , organic chemistry , coupling reaction , combinatorial chemistry
Solvent‐free synthesis of 3‐substituted indole derivatives by a one‐pot three‐component coupling reaction between aldehyde, N‐alkyl aniline and indole by Fe(HSO 4 ) 3 catalyzed is described. The noticeable features of this protocol are the simplicity of the procedure, easy synthesized, recyclable and inexpensive catalyst, no organic solvent and high yields in relatively short reaction times.