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Fabrication of Electrochemical Reduced Graphene Oxide Films on Glassy Carbon Electrode by Pulsed Potentiostatic Methods and Its Electrochemical Application
Author(s) -
Wang Yanwei,
Wu Yanju,
Zhao Chunlei,
Wang Fei
Publication year - 2014
Publication title -
journal of the chinese chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 45
eISSN - 2192-6549
pISSN - 0009-4536
DOI - 10.1002/jccs.201400189
Subject(s) - chronoamperometry , graphene , chemistry , cyclic voltammetry , baicalein , electrochemistry , oxide , electrode , redox , detection limit , glassy carbon , analytical chemistry (journal) , scanning electron microscope , differential pulse voltammetry , nuclear chemistry , inorganic chemistry , nanotechnology , materials science , chromatography , composite material , organic chemistry , biology , genetics
A graphene‐based electrochemical sensing platform for sensitive determination of baicalein was constructed by means of pulsed potentiostatic reduction of graphene oxide (GO) on a glassy carbon electrode (GCE). The resulting electrode (ERGO/GCE) was characterized by cyclic voltammetry (CV) and scanning electron microscopy (SEM). The electrochemical behaviors of baicalein at the ERGO/GCE were investigated in detail by CV, chronoamperometry (CA) and chronocoulometry (CC). The experimental results demonstrated that the ERGO/GCE exhibited excellent response toward the redox of baicalein as evidenced by the significant enhancement of redox peak currents ( i p ) and the decreased peak‐to‐peak separation (Δ E p ) in comparison with a bare GCE. Under the optimum experimental conditions, the reduction peak cureent was proportioanal to the baicalein concentration in the range of 5.0 × 10 ‐9 ∼ 5.0 × 10 ‐7 mol L ‐1 with the detection limit of 2.0 × 10 ‐9 mol L ‐1 . The proposed method was also applied successfully to determine baicalein in spiked human blood serum samples.