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Synthesis of β‐Haloketones by β‐Addition Reactions of α,β‐Unsaturated Ketones with BX 3 (X = Br, Cl) as Halide Source
Author(s) -
Lee Adam ShihYuan,
Wang ShuHuei,
Chang YuTing
Publication year - 2014
Publication title -
journal of the chinese chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 45
eISSN - 2192-6549
pISSN - 0009-4536
DOI - 10.1002/jccs.201300394
Subject(s) - chemistry , halide , ethylene glycol , ethylene , ketone , medicinal chemistry , organic chemistry , catalysis
A series of β‐bromoketones and β‐chloroketones were synthesized by the addition reactions of α,β‐unsaturated ketones under BX 3 (X = Br, Cl) and ethylene glycol reaction system. The α,β‐unsaturated ester also was successfully converted to its corresponding β‐bromoester under the reaction condition.