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Fe(NO 3 ) 3 ·9H 2 O as Efficient Catalyst for One‐pot Synthesis of Highly Functionalized Piperidines
Author(s) -
Hazeri Nourallah,
Maghsoodlou Malek Taher,
HabibiKhorassani Sayyed Mostafa,
Aboonajmi Jasem,
Sajadikhah Seyed Sajad
Publication year - 2013
Publication title -
journal of the chinese chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 45
eISSN - 2192-6549
pISSN - 0009-4536
DOI - 10.1002/jccs.201200421
Subject(s) - chemistry , catalysis , one pot synthesis , ethanol , column chromatography , organic chemistry , component (thermodynamics) , combinatorial chemistry , physics , thermodynamics
Fe(NO 3 ) 3 ·9H 2 O is used as an efficient and effective catalyst for the one‐pot three‐component synthesis of highly functionalized piperidines from aromatic aldehydes, anilines and b–ketoesters in ethanol at ambient temperature. This procedure includes some important aspects like the easy work‐up, no need to column chromatography, simple and readily available precursors, and good to high yields.