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Vitrifolin A: A Norlabdane Diterpenoid from the Fruits of Vitex trifolia Linn. var. simplicifolia Cham
Author(s) -
Zhang Teng,
Zhang Chong Xi,
Xie Wei Dong,
Row Kyung Ho
Publication year - 2013
Publication title -
journal of the chinese chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 45
eISSN - 2192-6549
pISSN - 0009-4536
DOI - 10.1002/jccs.201200239
Subject(s) - chemistry , terpenoid , vitex , nitric oxide , traditional medicine , terpene , stereochemistry , organic chemistry , medicine
A new norlabdane diterpenoid, named vitrifolin A, was isolated from the fruits of Vitex trifolia Linn. var. simplicifolia Cham. Its structure was elucidated by mean of spectroscopic methods, including HRESIMS, IR, 1D and 2D NMR. The inhibitory effect of vitrifolin A on nitric oxide production in lipopolysaccarideactivated mouse macrophages was also evaluated.