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A New, Fast and Easy Strategy for One‐pot Synthesis of Full Substituted Cyclopropanes: Direct Transformation of Aldehydes to 3‐Aryl‐1,1,2,2‐tetracyanocyclopropanes
Author(s) -
Pesyan Nader Noroozi,
Kimia Mohammad Ali,
Jalilzadeh Mohammad,
Şahin Ertan
Publication year - 2013
Publication title -
journal of the chinese chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 45
eISSN - 2192-6549
pISSN - 0009-4536
DOI - 10.1002/jccs.201200189
Subject(s) - chemistry , malononitrile , bromide , aryl , cyanogen bromide , combinatorial chemistry , mass spectrometry , transformation (genetics) , proton nmr , organic chemistry , catalysis , chromatography , biochemistry , alkyl , peptide sequence , gene
A new, fast and easy method for one‐pot reaction of aromatic aldehydes and dialdehydes with malononitrile and cyanogen bromide has been developed to afford full substituted 3‐arylcyclopropane‐1,1,2,2‐tetracarbonitriles in excellent yields in very short time (about 5 seconds). The structures elucidations werev characterized by IR, 1 H NMR, 13 C NMR, mass spectrometry and X‐ray crystallography techniques. For vthese compounds the crystallographic data showed two structures in mirror image in solid case and one distinct structure in solution. The reaction mechanism was discussed.