Premium
Synthesis, Characterization and Antimicrobial Activity of a New Aromatic Sulfonyl Hydrazone Derivative and Its Transition Metal Complexes
Author(s) -
Güzin Aslan H.,
Karacan Nurcan,
Aslan Ertuğrul
Publication year - 2013
Publication title -
journal of the chinese chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 45
eISSN - 2192-6549
pISSN - 0009-4536
DOI - 10.1002/jccs.201100580
Subject(s) - chemistry , hydrazone , antimicrobial , sulfonyl , transition metal , bacteria , nuclear chemistry , antifungal , metal , elemental analysis , magnetic susceptibility , agar diffusion test , derivative (finance) , stereochemistry , medicinal chemistry , organic chemistry , microbiology and biotechnology , crystallography , biochemistry , escherichia coli , catalysis , alkyl , financial economics , economics , genetics , biology , gene
Abstract In this study, benzenesulfonicacid‐1‐methylhydrazide ( bsmh ) derivatives such as 2‐hydroxy‐1‐naphtaldehydebenzenesulfonylhydrazone ( Hnafbsmh ) and its Ni(II), Pd(II), Pt(II), Cu(II), Co(II) complexes were synthesized. The structures of these complexes were investigated using elemental analyses (FT‐IR, LC‐MS, UV‐VIS), magnetic susceptibility and conductivity measurement techniques. The complexes were found to have general compositions [ML 2 ]. All the synthesized complexes were evaluated in vitro as antimicrobial agents against representative strains of six gram‐positive and four gram‐negative bacteria and as an antifungal agent by disc diffusion methods. All the bacteria and fungi studied were screened against some commercial antibiotics to compare them with our chemical's zone diameters.