Two New 4‐Hydroxyisoflavanes from the Root of  Codonopsis cordifolioidea  and Their Anti‐virus Activities | Zendy

Gao Xuemei | Zendy; Mu Huaixue | Zendy; Li Xuesen | Zendy; Yang Guangyu | Zendy; Li Ganpeng | Zendy; Hu Qiufen | Zendy

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Two New 4‐Hydroxyisoflavanes from the Root of Codonopsis cordifolioidea and Their Anti‐virus Activities

Author(s) -

Gao Xuemei,

Mu Huaixue,

Li Xuesen,

Yang Guangyu,

Li Ganpeng,

Hu Qiufen

Publication year - 2012

Publication title -

journal of the chinese chemical society

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.329

H-Index - 45

eISSN - 2192-6549

pISSN - 0009-4536

DOI - 10.1002/jccs.201100525

Subject(s) - chemistry , tobacco mosaic virus , codonopsis , virus , stereochemistry , virology , medicine , alternative medicine , traditional chinese medicine , pathology , biology

Two new 4‐hydroxyisoflavanes, cordifoliflavanes A and B (1 and 2), were isolated from the roots of Codonopsis cordifolioidea . Their structures were elucidated by spectroscopic methods, including extensive 1D‐ and 2D‐NMR techniques. Compounds 1 and 2 were tested for their anti‐HIV‐1 activities and anti‐tobacco mosaic virus activities. The results showed that compounds 1 and 2 have modest anti‐HIV‐1 activities and anti‐tobacco mosaic virus activities, respectively.

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