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Catalyst Free Indirect Friedländer Synthesis of Substituted Quinolines from Alcohols in PEG‐400
Author(s) -
Wu FangWen,
Hou ReiSheu,
Wang HueyMin,
Kang IouJiun,
Chen LingChing
Publication year - 2012
Publication title -
journal of the chinese chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 45
eISSN - 2192-6549
pISSN - 0009-4536
DOI - 10.1002/jccs.201100404
Subject(s) - chemistry , catalysis , peg 400 , ketone , peg ratio , base (topology) , transition metal , organic chemistry , combinatorial chemistry , polymer chemistry , polyethylene glycol , mathematical analysis , mathematics , finance , economics
The synthesis of substituted quinolines can be easily and greenly accomplished by the direct reaction between the corresponding aminoalcohol and ketone using PEG‐400 as reaction medium in the presence of a base, without any transition‐metal catalyst.