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Studies on Suzuki‐Miyaura Reactions Catalyzed by Ferrocenyl or Cobaltocenyl Phosphines Ligated Palladium Complexes
Author(s) -
Hsiao Jun,
Weng ChiaMing,
Hong FungE
Publication year - 2012
Publication title -
journal of the chinese chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 45
eISSN - 2192-6549
pISSN - 0009-4536
DOI - 10.1002/jccs.201100342
Subject(s) - chemistry , palladium , phosphine , denticity , catalysis , medicinal chemistry , suzuki reaction , stereochemistry , organic chemistry , metal
DFT studies on several dppf ‐ and dppc ‐derived bidentate phosphines ligated palladium complexes catalyzed Suzuki‐Miyaura coupling reactions were pursued. The catalytic reactions employing ligands, having two phosphine biting sites on different cyclpentadienyl or cyclobutadiene rings, such as 1,1′‐dmpf or 1,1′‐dmpc , have been verified to be energetically more favorable than those on the same ring provided that tetra‐coordinated palladium conformations for all transition states and intermediates are maintained. Apart from the purpose of storage, the application of phosphinous acid (R 2 P(OH)) in Suzuki‐Miyaura reaction is inferior to tertiary phosphine (R 3 P).