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Xanthan Sulfuric Acid as an Efficient Biodegradable and Recyclable Catalyst for the One‐Pot Synthesis of α‐Amino Phosphonates
Author(s) -
Sun GuoYing,
Hou JunTao,
Dou JingJie,
Lu Jun,
Hou YongJie,
Xue Tuo,
Zhang ZhanHui
Publication year - 2010
Publication title -
journal of the chinese chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 45
eISSN - 2192-6549
pISSN - 0009-4536
DOI - 10.1002/jccs.201000194
Subject(s) - chemistry , sulfuric acid , catalysis , solid acid , condensation , organic chemistry , amine gas treating , solvent , amino acid , one pot synthesis , biochemistry , physics , thermodynamics
A convenient and efficient procedure for the synthesis of α‐amino phosphonates by a one‐pot, three‐component condensation of aldehydes, amine, and diethyl phosphite in the presence of xanthan sulfuric acid as a bio‐supported catalyst under solvent‐free conditions has been developed. A wide range of α‐amino phosphonates have been obtained in high to excellent yields. Furthermore, the catalyst can be recovered simply and reused several times in subsequent reactions.