Facile Access to Benzothiazole‐Containing Pyrrolo[1,2‐ a ]quinolines and Pyrrolo[2,1‐ a ]isoquinolines  via  Nitrogen Ylides | Zendy

Dawood Kamal M. | Zendy; Ragab Eman A. | Zendy; Khedr Nabila A. | Zendy

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Facile Access to Benzothiazole‐Containing Pyrrolo[1,2‐ a ]quinolines and Pyrrolo[2,1‐ a ]isoquinolines via Nitrogen Ylides

Author(s) -

Dawood Kamal M.,

Ragab Eman A.,

Khedr Nabila A.

Publication year - 2009

Publication title -

journal of the chinese chemical society

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.329

H-Index - 45

eISSN - 2192-6549

pISSN - 0009-4536

DOI - 10.1002/jccs.200900170

Subject(s) - benzothiazole , isoquinoline , chemistry , quinoline , acetylene , benzene , medicinal chemistry , cycloaddition , ethylene , nitrogen , organic chemistry , catalysis

Quinoline and isoquinoline react with 2‐(bromoacetyl)benzothiazole ( 1 ) in dry benzene to give the corresponding quinolinium and isoquinolinium salts 2 and 10 which undergo base‐mediated [3+2] 1,3‐dipolar cycloaddition with some acetylene and ethylene derivatives to give the corresponding benzothiazole‐containing pyrrolo[1,2‐ a ]quinoline and pyrrolo[2,1‐ a ]isoquinoline derivatives.

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