A Simple and Efficient Procedure for Synthesis of Optically Active 1,2,4‐Triazolo‐[3,4‐ b ]‐1,3,4‐Thiadiazole Derivatives Containing  l ‐Amino Acid Moieties | Zendy

Foroughifar Naser | Zendy; Mobinikhaledi Akbar | Zendy; Ebrahimi Sattar | Zendy; Fard Mohammad Ali Bodaghi | Zendy; Moghanian Hassan | Zendy

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A Simple and Efficient Procedure for Synthesis of Optically Active 1,2,4‐Triazolo‐[3,4‐ b ]‐1,3,4‐Thiadiazole Derivatives Containing l ‐Amino Acid Moieties

Author(s) -

Foroughifar Naser,

Mobinikhaledi Akbar,

Ebrahimi Sattar,

Fard Mohammad Ali Bodaghi,

Moghanian Hassan

Publication year - 2009

Publication title -

journal of the chinese chemical society

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.329

H-Index - 45

eISSN - 2192-6549

pISSN - 0009-4536

DOI - 10.1002/jccs.200900151

Subject(s) - chemistry , optically active , amino acid , thiadiazoles , proton nmr , elemental analysis , stereochemistry , organic chemistry , combinatorial chemistry , biochemistry

Some new and optically active 1,2,4‐triazolo thiadiazoles bearing N ‐phthaloyl‐ l ‐amino acids were synthesized by reaction of 4‐amino‐5‐(3‐ or 4‐)pyridyl‐3‐mercapto‐(4 H )‐1,2,4‐triazoles with N ‐phthaloyl‐ l ‐amino acids in the presence of phosphorus oxychloride. All the newly synthesized compounds were confirmed by IR, 1 H NMR, 13 C NMR and elemental analysis.

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