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Polar Constituents from Sageretia Thea Leaf Characterized by HPLC‐SPE‐NMR Assisted Approaches
Author(s) -
Shen CaJane,
Chen ChienKuang,
Lee ShoeiSheng
Publication year - 2009
Publication title -
journal of the chinese chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 45
eISSN - 2192-6549
pISSN - 0009-4536
DOI - 10.1002/jccs.200900146
Subject(s) - chemistry , myricetin , high performance liquid chromatography , chromatography , glycoside , quercetin , fraction (chemistry) , stereochemistry , organic chemistry , kaempferol , antioxidant
Nine glycosides ( 1–9 ) were characterized from the n ‐butanol‐soluble fraction of the ethanolic extract of the leaves of Sageretia thea by the general approach. Among these, Compounds 6 and 7 were identified as a mixture. Application of HPLC‐SPE‐NMR in two selected fractions led to the separation of this mixture and the characterization of three additional minors ( 10–12 ). Among these, 7‐ O ‐methylmyricetin 3‐ O ‐α‐ l ‐arabinofuranoside ( 8 ) is a new natural product and eight compounds, i.e. glucofragulin A ( 1 ), quercetin‐3‐ O ‐α‐ l ‐arabinopyranoside ( 5 ), 3‐ O ‐β‐ d ‐galactopyranoside ( 6 ), 3‐ O ‐β‐ d ‐glucopyranoside ( 7 ), and 3‐ O ‐α‐ l ‐arabinofuranoside ( 11 ), myricetin‐3‐ O ‐α‐ l ‐arabinofuranoside ( 9 ) and 3‐ O ‐β‐ d ‐glucopyranoside ( 10 ), and quercetrin ( 12 ), are found for the first time from the title plant.