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Bipyridine‐Modulated Palladium‐Catalyzed Oxidative Heck‐Type Reactions of Arylboronic Acids with Olefins
Author(s) -
Hsu ChienMing,
Li ChihBin,
Sun ChiaHsing
Publication year - 2009
Publication title -
journal of the chinese chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 45
eISSN - 2192-6549
pISSN - 0009-4536
DOI - 10.1002/jccs.200900129
Subject(s) - chemistry , palladium , catalysis , heck reaction , ligand (biochemistry) , bipyridine , oxidative phosphorylation , chelation , biphenyl , medicinal chemistry , oxidative addition , organic chemistry , receptor , crystal structure , biochemistry
We have demonstrated that 4,4′‐dimethyl 2,2′‐bipyridine as ligand for Pd(II) catalysts was very efficient for oxidative Heck‐type coupling reaction of arylboronic acids with olefins in DMA or CH 3 CN under atm air at 80 °C. The presence of chelated bipyridine ligand isindispensable to achieve high reaction yields and to suppress the formation of biphenyl as homocoupled byproduct.