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Three‐Component One‐Pot Synthesis of Indeno[2′,1′:5,6]Pyrido[2,3‐ d ]Pyrazole Derivatives in Aqueous Media
Author(s) -
Shi DaQing,
Shi JingWen,
Yao Hao
Publication year - 2009
Publication title -
journal of the chinese chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 45
eISSN - 2192-6549
pISSN - 0009-4536
DOI - 10.1002/jccs.200900075
Subject(s) - chemistry , pyrazole , aldehyde , aqueous medium , aqueous solution , component (thermodynamics) , mass spectrum , proton nmr , stereochemistry , medicinal chemistry , mass spectrometry , organic chemistry , chromatography , catalysis , physics , thermodynamics
A series of indeno[2′,1′:5,6]pyrido[2,3‐ d ]pyrazoles was synthesized by the three‐component reaction of aldehyde, 5‐amino‐3‐methyl‐1‐phenylpyrazole and 1,3‐indenedione in the presence of SDS in aqueous media. The structures were characterized by IR, 1 H NMR, high resolution mass spectra and were further confirmed by X‐ray diffraction analysis.