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Selective and Convenient Protection of Aldehydes as Azines under Solvent‐Free Conditions
Author(s) -
Eshghi Hossein,
Hosseini Mosayyeb
Publication year - 2008
Publication title -
journal of the chinese chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 45
eISSN - 2192-6549
pISSN - 0009-4536
DOI - 10.1002/jccs.200800093
Subject(s) - chemistry , hydrazine (antidepressant) , ferric , solvent , selectivity , simplicity , chloride , reaction conditions , combinatorial chemistry , organic chemistry , catalysis , chromatography , philosophy , epistemology
Aldehydes can be easily protected as azines in the presence of hydrazine monohydrochloride and ferric chloride under solvent‐free conditions. The major advantages of this method are: operational simplicity, ready availability, selectivity, general applicability, mild reaction conditions with low cost of the reactants, short reaction times and excellent yields.