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Bis ‐Bromine‐1,4‐Diazabicyclo[2.2.2]Octane (Br 2 ‐DABCO) as an Efficient Promoter for One‐Pot Conversion of N ‐Arylglycines to N ‐Arylsydnones in the Presence of NaNO 2 /Ac 2 O Under Neutral Conditions
Author(s) -
GhasemnejadBosra Hassan,
Haghdadi Mina,
Khanmohammade Omid,
Gholipour Abdoreza M.,
Asghari Gharibreza
Publication year - 2008
Publication title -
journal of the chinese chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 45
eISSN - 2192-6549
pISSN - 0009-4536
DOI - 10.1002/jccs.200800069
Subject(s) - dabco , chemistry , octane , bromine , nitrosation , medicinal chemistry , organic chemistry
Bis ‐Bromin‐1,4‐diazabicyclo[2.2.2]octane (Br 2 ‐DABCO)‐promoted one‐pot conversion of various N ‐arylglycines to sydnones using a combination of NaNO 2 and Ac 2 O has been achieved efficiently through N ‐nitrosation followed by cyclization in high yields (90‐96%) under mild and neutral conditions.