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Synthesis of N ‐Tosylhomosphinganine and N ‐Tosylsedridine
Author(s) -
Chang MengYang,
Lin ChunYu,
Wu TsunCheng,
Sun PeiPei
Publication year - 2008
Publication title -
journal of the chinese chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 45
eISSN - 2192-6549
pISSN - 0009-4536
DOI - 10.1002/jccs.200800063
Subject(s) - chemistry , regioselectivity , ring closing metathesis , grignard reaction , metathesis , salt metathesis reaction , stereochemistry , ring (chemistry) , combinatorial chemistry , organic chemistry , catalysis , polymer , reagent , polymerization
A straightforward synthesis of N ‐tosylhomosphinganine and N ‐tosylsedridine has been achieved from trans ‐4‐hydroxyproline by Grignard addition, regioselective Baeyer‐Villiger reaction, cross or ring‐closing metathesis and hydrogenation as the key steps.