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Electrode Kinetics and Complex Formation of [Zn‐Antibiotics‐Cephalothin] System vis a vis Kinetics of Electrode Reactions
Author(s) -
Khan Farid
Publication year - 2007
Publication title -
journal of the chinese chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 45
eISSN - 2192-6549
pISSN - 0009-4536
DOI - 10.1002/jccs.200700096
Subject(s) - chemistry , kinetics , reaction rate constant , tetracycline , electrode , analytical chemistry (journal) , standard hydrogen electrode , oxytetracycline , inorganic chemistry , reference electrode , antibiotics , electrochemistry , chromatography , biochemistry , physics , quantum mechanics
Charge transfer reactions between a dropping mercury electrode and a [Mn‐antibiotics‐cephalothin] system were studied at pH = 7.30 ± 0.01, μ = 1.0 MNaClO 4 at 298 K. The antibiotics were doxycycline, chlortetracycline, oxytetracycline, tetracycline, minocycline, amoxicillin and chloramphenicol used as primary ligands and cephalothin as secondary ligand formed 1:1:1, 1:1:2 and 1:2:1 complexes with Zn 2 . Electrode kinetics was discussed on the basis of kinetic parameters viz. transfer coefficient (α), degree of irreversibility (λ), diffusion coefficient (D) and rate constant (k). The values of α varied from 0.40 to 0.57 (0.50) confirm that ‘transition state’ behaves between reactant and product response to applied potential and it lies always between d.m.e. and solution interface. A small variation in potential affects the rate and rate constant greatly.