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Synthesis of Deuterium Labeled (±)‐2,5‐Dimethoxyamphetamine (DMA), (±)‐4‐Bromo‐2,5‐Dimethoxyamphetamine (DOB), and (±)‐4‐Methoxyamphetamine (PMA) as Internal Standards for Quantitative Analyses by GC‐MS
Author(s) -
Xu YaZhu,
Lin HueiRu,
Lua ChangAhai,
Chen Chinpiao
Publication year - 2007
Publication title -
journal of the chinese chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 45
eISSN - 2192-6549
pISSN - 0009-4536
DOI - 10.1002/jccs.200700070
Subject(s) - chemistry , gas chromatography–mass spectrometry , mass spectrometry , deuterium , gas chromatography , chromatography , physics , quantum mechanics
Abstract DMA, DOB and PMA are increasingly abused central nervous system stimulants with neurotoxic properties. In recent years, many controlled substance analogs (designer drugs) with a large variety of structures have reached the illegal market, making their identification difficult. Therefore, this work studies the synthesis of DOB‐d 6 , DMA‐ d 6 and PMA‐ d 3 as internal standards for use in gas chromatography‐mass spectrometry (GC‐MS) to identify controlled substances.