New Triheterocyclic Ring System. Synthesis of Functionalized Pyrazolo[3,4‐d]Pyrimido[1,2‐b][1,2,4,5]Tetrazine Derivatives | Zendy

Mosselhi Mosselhi A. N. | Zendy; Hussein Ahmad M. | Zendy; Shawali Ahmad Sami | Zendy

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New Triheterocyclic Ring System. Synthesis of Functionalized Pyrazolo[3,4‐d]Pyrimido[1,2‐b][1,2,4,5]Tetrazine Derivatives

Author(s) -

Mosselhi Mosselhi A. N.,

Hussein Ahmad M.,

Shawali Ahmad Sami

Publication year - 2006

Publication title -

journal of the chinese chemical society

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.329

H-Index - 45

eISSN - 2192-6549

pISSN - 0009-4536

DOI - 10.1002/jccs.200600123

Subject(s) - chemistry , tetrazine , regioselectivity , ring (chemistry) , halide , derivative (finance) , medicinal chemistry , stereochemistry , combinatorial chemistry , organic chemistry , catalysis , financial economics , economics

New functionalized pyrazolo[3,4‐d]pyrimido[1,2‐b][1,2,4,5]tetrazine derivatives 6a‐q were synthesized via reaction of the hydrazonoyl halides 1a‐q with 5‐amino‐1‐phenyl‐6‐thioxo‐pyrazolo[3,4‐d]pyrimidin‐4‐one 2 and its 2‐methylthio derivative 3 . The mechanism and the regioselectivity of the studied reactions have been discussed.

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