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Synthesis and Cytotoxicity Studies of Cyclohepta[ b ]indoles, Benzo[6,7]Cyclohepta[1,2‐ b ]Indoles, Indeno[1,2‐ b ]Indoles, and Benzo[ a ]Carbazoles
Author(s) -
Hong BorCherng,
Jiang YeaFen,
Chang YiLing,
Lee ShiowJu
Publication year - 2006
Publication title -
journal of the chinese chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 45
eISSN - 2192-6549
pISSN - 0009-4536
DOI - 10.1002/jccs.200600086
Subject(s) - chemistry , cytotoxicity , stereochemistry , tricyclic , indole test , in vitro , biochemistry
Synthesis and biological evaluation of various tricyclic and tetracyclic indoles are described. A number of these compounds possess in vitro activity against human nasopharyngeal carcinoma (HONE‐1) and gastric adenocarcinoma (NUGC‐3) cell lines.